Guillaume Dubois (6 September 1656 – 10 August 1723) was a French cardinal and statesman. When the Duc D'Orléans became regent (1715) Dubois, who had for some years acted as his secretary, was made councillor of state, and the chief power passed gradually into his hands. Dubois' policy was steadily directed towards maintaining the peace of Utrecht, and this made him the main opponent of the schemes of Cardinal Alberoni for the aggrandizement of Spain. To counteract Alberoni's intrigues, he suggested an alliance with Britain and in the face of great difficulties succeeded in negotiating the Triple Alliance (1717). In 1719 he sent armies into Spain as part of the Quadruple Alliance which forced Philip V to dismiss Alberoni. Otherwise his policy remained that of peace. Dubois' success strengthened him against the bitter opposition of a large section of the court.

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